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Nature Made® SAM-e 200 mg - 90 Enteric Coated Tablets

3.8 out of 5 stars 30 customer reviews
About the Product
  • Nature Made Sam - E Complete Healthy Mood and Joint Comfort 200mg Tablets 90 Tablets per Bottle
  • Clinically proven for healthy mood and joint comfort.
  • Naturally restores a healthy mood.

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Product Details

  • Product Dimensions: 4 x 3 x 3 inches
  • Shipping Weight: 2 pounds
  • ASIN: B000GB7OFM
  • UPC: 031604011031
  • Average Customer Review: 3.8 out of 5 stars  See all reviews (30 customer reviews)
  • Amazon Best Sellers Rank: #341,937 in Health & Personal Care (See Top 100 in Health & Personal Care)
    • Product Warranty: For warranty information about this product, please click here

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Customer Reviews

Top Customer Reviews

5.0 out of 5 starsWorks Well but Has Misconceptions
By Pwoink on September 30, 2009
Verified Purchase
Sam-E has worked well for me, after I knew how to take it properly that is. I took it for about 2 weeks before I actually did some reading about it and knew I was doing many things wrong. Including making the wrong purchase. Any brand will probably do, (as long as it is made properly, see #2 below) but I have found Nature Made to be the best selection when it came to purchasing Sam-E. (Yes, I have actually bought and tried the 200mg tablets) No matter what brand you buy, you have to give it TIME to work. 7-10 days is the timeframe that it will typically start to work in, but I have heard of occasions where it has taken longer. After 12 days if you have seen no positive change in mood, up the dose. Eventually, work your way up to taking 1200mg of Sam-E daily for best results.

Stomach Cramps and even the possibility of ulcers be a serious problem for people taking Sam-E. I have compiled a list of precautions and things you can do to prevent this:

1) Make sure you take this product on an EMPTY STOMACH. An empty stomach means not having eaten anything for roughly an hour. The best time to take this is in the morning, right after waking up. Finally, make sure you do not eat for at least 30 MINUTES after taking Sam-e. More time may be required as you take more of the supplement.

2) Do NOT purchase Sam-E tablets that are not enteric coated and are not in a box/blister wrap. The Entric coating prevents the pills from being absorbed by your body until they reach the lower intestine which will prevent a majority of stomach cramps and stomach pains. Not only this, but it will prevent the Sam-E from being dissolved in the stomach which renders it virtually useless.Read more ›
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5.0 out of 5 starsPositive Experience
By Darlene Whiteman on May 17, 2007
Verified Purchase
I was a little doubtful about taking this supplement, but I have been suffering from mild depression and sleeplessness and didn't want to start on a prescription antidepressant. After a week of taking this product, I found that I was handling stess much better than usual. I encountered an extremely difficult situation in my personal life and found that I did not "go to pieces," but handled it in a calm and confident manner. I didn't even cry (which would normally have been my first response). I am also sleeping better and feeling more rested. I plan to continue taking this supplement.
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5.0 out of 5 starsThe better brand for this, I believe
By MW VINE VOICE on November 6, 2008
I gave SAM-e a try, and bought this Nature Made Complete brand (200 mg). I noticed a positive difference in my mood and energy level. I don't mean that I felt an overwhelming since of euphoria or anything like that...at least that wasn't the case from my experience. The difference was subtle, yet noticiable. I didn't tell my wife I had started taking it, yet she also noticed the difference. I decided to keep taking it, and switched over to Source Naturals, a slightly less expensive option at the time.

I do believe there is a difference in what you get. I have noticed no benefit at all from the Source Naturals brand. I'll continue to take it since I paid for it, but I wish I had stayed with Nature Made and will switch back over to them once these are gone. (no, I do not work for Nature Made!)
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5.0 out of 5 starsIF I COULD AWARD SAM-e TEN STARS, I WOULD
By David R. Eastwood on November 19, 2010
Writing as an ex-Army officer and a retired university professor who has had three serious surgeries and suffered more than a dozen deaths of family members and friends in the past decade, some of my depression was "situational." Additionally, for over 60 years I had also suffered from a relatively mild chronic depression that I self-treated with exercise, music, and meditation.

About three years ago, my own remedies were no longer sufficent--a dozen times a day I would find myself thinking or whispering to myself, "I wish I were just dead." By luck, I stumbled across an article that mentioned SAM-e, and by further luck I had a friend (a neuro-scientist at Stanford Univ.) that I could e-mail and ask if he'd ever heard of it. He replied that Richard Brown, a friend of his at Cornell Univ., had co-written a book, STOP DEPRESSION NOW, which would give me more answers than he could. I bought the book, read it, and then tried SAM-e.

I began with 200 mg. of SAM-e, and within two weeks my depression was greatly relieved--it was as if a heavy layer of ice which was pressing down on the roof of a house had suddenly melted and slid off. Within four weeks, at a slightly higher dosage of SAM-e, my depression was totally gone. Of course problems and feelings of grief were still there, but I was able to deal with them without dark feelings of hopelessness getting in my way.

Very properly, Nature Made has put a "CAUTION" notice on the side of the box: "People with bipolar (manic) depression should not take this or any other product containing SAM-e except under a doctor's supervision." HOWEVER, the print is rather small--my recommendation is that they state this warning in larger, bold-face type.

In my judgment, based on my experience, SAM-e deserves to be awarded 10 stars.
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5.0 out of 5 starsAmazing!
By J. Gustafson on August 4, 2007
Verified Purchase
Several years ago I had a sudden flare up of sciatica with pain in my lower back and down my right leg. It was difficult to sit or walk and nothing seemed to be helping. I've been taking 2 tabs daily now and have been pain free nearly 3 years. What a relief!
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Most Recent Customer Reviews

5.0 out of 5 starsSafe mood elevator. No side effects.

My husband and I Have taken this supplement for over 10 years. Works great for "mood".

Published 12 months ago by Picasso
3.0 out of 5 starsThree Stars

Didn't work all that well for me, but it seems to work wonders for other folks.

Published 19 months ago by Kelli Page
4.0 out of 5 starsFour Stars

great

Published 21 months ago by Charles A. Beaird
5.0 out of 5 starsGood Product

With the tough economic times, I have experienced more stress and a negative attitude. I believe the SAM-e helps lighten my mood a bit.

Published on February 12, 2013 by Ladymorningstar
5.0 out of 5 starsReally helps me

Sam-e has been working for me for some months now. You do have to figure out what dosage works for you. Some people seem to get anxious if they take too much. Read more

Published on September 30, 2012 by Barb V.
5.0 out of 5 starsTHIS STUFF IS SAM-EZING

This stuff works wonders!

I went through a pretty rough patch in my life. I lost 2 dogs, 1 cat, and my best friend/roommate to cancer all within 2 years. Read more

Published on September 11, 2012 by Simmer
5.0 out of 5 starsTHIS STUFF IS SAM-EZING

This stuff works wonders!

I went through a pretty rough patch in my life. I lost 2 dogs, 1 cat, and my best friend/roommate to cancer all within 2 years. Read more

Published on September 11, 2012 by Simmer
5.0 out of 5 starsLove my Sam-e!

I've been taking the supplement SAM-e for about a year. It has really helped me feel more grounded, less stressed out. Read more

Published on December 3, 2011 by birdy43
4.0 out of 5 starsProduct worked very well for my moderate depression

I tried Nature Made Sam-e with much skepticism.I reached a point where I knew medication was needed to treat my depressive state, but I was terrified of the idea of going on a... Read more

Published on November 29, 2011 by Erica
5.0 out of 5 starsGreat stuff works well!

I have noticed a remarkable difference in my mood while taking Sam-E. I highly recommend it even though it's a bit pricey, the benefits are worth it.

Published on November 17, 2010 by Anne

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